41 Results for "

Cistus symphytifolius Lam.

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "Cistus symphytifolius Lam." in MCE Product Catalog:

44
44 Cited Publications
Art. -Nr.: HY-14644
CAS. Nr.: 541550-19-0
Reinheit:  99.80%
Synonyms: STA 5326; LAM-002A free base; AIT-101
Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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44
44 Cited Publications
Art. -Nr.: HY-14644A
CAS. Nr.: 870087-36-8
Reinheit:  99.83%
Synonyms: STA 5326 mesylate; LAM-002A; AIT-101 mesylate
Forschungsgebiete:  

Inflammation/Immunology Cancer

Apilimod (STA 5326) mesylate is a potent IL-12/IL-23 inhibitor, and strongly inhibits IL-12 with IC50s of 1 nM and 2 nM, in IFN-γ/SAC-stimulated human PBMCs and SAC-treated monkey PBMCs, respectively . Apilimod is a potent and highly selective PIKfyve inhibitor.
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Art. -Nr.: HY-129467
CAS. Nr.: 56472-29-8
Reinheit:  ≥98.0%
Synonyms: 2-Hydroxyoleic acid; 2-OHOA; LAM561
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect .
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Art. -Nr.: HY-150229
CAS. Nr.: 2803699-70-7
Reinheit:  98.84%
306-N16B is a selective lung-targeted lipid nanoparticle that reversibly targets lung endothelial cells and specific immune cells through selective adsorption of a protein corona mediated by differences in tail structure (such as fibrinogen β/γ chain). 306-N16B binds to specific plasma proteins in the blood to form a protein corona, which guides the particles to be enriched in the lungs, releases mRNA and promotes target cell gene expression, exerts efficient lung cell transfection activity, and can precisely regulate gene delivery of different cell types in the lungs (such as endothelial cells and macrophages). 306-N16B can be used in gene therapy technologies for hereditary lung diseases including pulmonary lymphangioleiomyomatosis (LAM), restoring tumor suppressor function by delivering Tsc2 mRNA, and can also be used for lung-specific mRNA vaccines and gene editing therapies .
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Art. -Nr.: HY-N8503
CAS. Nr.: 147821-49-6
Niazimicin can be isolated from seeds and leaves of Moringa oleifera Lam. Niazimicin is thiocarbamate compound .
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Art. -Nr.: HY-N10842
CAS. Nr.: 88140-31-2
6-Formyllimetin is a natural product isolated from the root bark of T. asiatica LAM .
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Art. -Nr.: HY-N10803
CAS. Nr.: 15575-50-5
(+)-6-(3-Chloro-2-hydroxy-3-methylbutyl)-5,7-dimethoxycoumarin is a nature product that could be isolated form the root bark of Toddalia asiatica (L.) LAM .
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Art. -Nr.: HY-164915
CAS. Nr.: 1218932-97-8
Target:  

Bacterial

Forschungsgebiete:  

Metabolic Disease

5-InoAz is an inositol analogue containing an azide group, which is used as a metabolic probe for labeling the mycobacterial cell envelope. 5-InoAz integrates into cell envelope glycolipids [phosphatidylinositol mannoside (PIM), PIM-anchored lipomannan (LM), and lipoarabinomannan (LAM)] .
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Art. -Nr.: HY-N9097
CAS. Nr.: 122001-32-5
Niazirin is an orally active antioxidant. Niazirin can be isolated from Moringa oleifera Lam. Niazirin reduces the production levels of ROS and MDA, while increasing the levels of superoxide dismutase SOD and glutathione peroxidase GPx. Niazirin also abolishes high glucose-induced PKCζ activation and inhibits Nox4 protein expression. Niazirin exhibits excellent free radical scavenging activity. Niazirin significantly inhibits high glucose-induced proliferation of vascular smooth muscle cells. Niazirin can be used in the research of diabetic atherosclerosis .
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Art. -Nr.: HY-N0080
CAS. Nr.: 28095-18-3
Synonyms: Peucedanol methyl ether
Ulopterol is a coumarin isolated from the leaves of Toddalia asiatica (L.) Lam with potent antibacterial and antifungal activities .
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Art. -Nr.: HY-14644B
CAS. Nr.: 870087-37-9
Synonyms: STA 5326 hydrochloride; LAM-002A free base hydrochloride; AIT-101 hydrochloride
Forschungsgebiete:  

Infection Inflammation/Immunology

Apilimod (STA 5326) hydrochloride is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation and IL-1β secretion. Apilimod hydrochloride has been shown to inhibit host cell proteases, which may prevent viral invasion but also block antiviral immune responses, potentially exacerbating immunosuppression in COVID-19.
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Art. -Nr.: HY-N3411
CAS. Nr.: 10267-31-9
Synonyms: 13E-Labdene-8α,15-diol; Copal-8α,15-diol
Labd-13(E)-ene-8α,15-diol is a diterpene with the labdane skeleton which can be extracted from Cistus symphytijbfolius .
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Art. -Nr.: HY-N20464
Category:  

Extract

Target:  

Others

Cistus incanus extract is an extract of a Mediterranean shrub (Cistus incanus L.) that is rich in polyphenols and has significant antioxidant activity.
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Art. -Nr.: HY-N3652
CAS. Nr.: 51593-96-5
Cuspidiol (compound 3) is a CH2Cl2 extract of Fagara zanthoxyloides Lam. Cuspidiol has antifungal and antioxidative activity .
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Art. -Nr.: HY-N9538
CAS. Nr.: 55481-87-3
8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin that can be found in Heracleum pyrenaicum Lam.
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Art. -Nr.: HY-N12351
CAS. Nr.: 624739-20-4
Ellagic acid 4-O-α-L-arabinopyranoside, isolated from longan Dimocarpus longan Lour, syn. Euphoria longan Lam. has antioxidative activity .
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Art. -Nr.: HY-129467A
CAS. Nr.: 1229114-68-4
Synonyms: 2-Hydroxyoleic acid sodium; 2-OHOA sodium; LAM561 sodium
Target:  

Apoptosis

Forschungsgebiete:  

Cancer

(Rac)-Idroxioleic acid (2-Hydroxyoleic acid) sodium is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid sodium has anti-tumor effect .
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Art. -Nr.: HY-139784
CAS. Nr.: 182370-45-2
Synonyms: (R)-2-Hydroxyoleic acid; (R)-2-OHOA; (R)-LAM561
Target:  

Endogenous Metabolite

Forschungsgebiete:  

Cancer

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities .
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Art. -Nr.: HY-129467R
CAS. Nr.: 56472-29-8
Synonyms: 2-Hydroxyoleic acid (Standard); 2-OHOA (Standard); LAM561 (Standard)
Forschungsgebiete:  

Cancer

(Rac)-Idroxioleic acid (Standard) is the analytical standard of (Rac)-Idroxioleic acid. This product is intended for research and analytical applications. (Rac)-Idroxioleic acid (2-Hydroxyoleic acid) is a synthetic oleic acid (OA) derivative that binds to the plasma membrane and alters lipid organization. (Rac)-Idroxioleic acid has anti-tumor effect[1].
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Art. -Nr.: HY-118362
CAS. Nr.: 113579-07-0
Target:  

Bacterial

Forschungsgebiete:  

Infection

Netzahualcoyonol is a quinone methyl triterpene isolated from the roots of Salacia multiflora (Lam.) DC. Netzahualcoyonol exhibits antibacterial and anti-biofilm activities. Netzahualcoyonol inhibits Gram-positive bacteria (MIC=3.26–52 μM). Additionally, Netzahualcoyonol demonstrates cytotoxicity against Hep G2 cells (IC50 = 1.95 μM) but exhibits low toxicity towards Vero cells .
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